rat igg2b apc Search Results


apc conjugated rat igg2b isotype control  (R&D Systems)
90
R&D Systems apc conjugated rat igg2b isotype control
Apc Conjugated Rat Igg2b Isotype Control, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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apc conjugated rat igg2b  (Elabscience Biotechnology)
93
Elabscience Biotechnology apc conjugated rat igg2b
Apc Conjugated Rat Igg2b, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti pou3f2  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology anti pou3f2
Anti Pou3f2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rat r d systems ic013a  (R&D Systems)
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Rat R D Systems Ic013a, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gr 1  (Cedarlane)
85
Cedarlane gr 1
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rat isotype igg2a apc  (Cytek Biosciences)
93
Cytek Biosciences rat isotype igg2a apc
Rat Isotype Igg2a Apc, supplied by Cytek Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ab 884527 rat igg2b apc  (R&D Systems)
92
R&D Systems ab 884527 rat igg2b apc
Figure 4. Fc effector-enhanced anti-TREM2 mAb therapy reverses anti-PD-1 resistance (A) Frequency of live TREM2+ target cells following co-culture with mouse BMDMs and varying amounts of anti-TREM2-WT (mouse immuno- globulin G2a <t>[IgG2a])</t> or anti-TREM2 (afucosylated mouse IgG2a) (n = 4/group). Samples were com- bined from two independent experiments. (B) ADCC reporter cell fluorescence following co- culture with or ADCC reporter cells and TREM2+- expressing target cells and varying amounts of anti-TREM2-WT, anti-TREM2, or appropriate iso- types (n = 2/group). (C) Tumor growth of EMT6-tumor bearing animals treated with 5 mg/kg of isotype or anti-TREM2. Vertical dotted lines indicate days when mAb dosing occurred (n = 10/group). (D) Violin plots of intratumoral normalized TAMs as a frequency of CD45+ cells from isotype- and anti- TREM2-treated EMT6 tumor-bearing mice 24, 72, and 128 h after mAb treatment. Samples were combined from two independent experiments (experiment 1, n = 4–7/group; experiment 2, n = 10/group). Unless specified otherwise, all experiments were performed two or more times. For graphs with error bars, mean ± SEM is shown. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. See also Figure S4.
Ab 884527 Rat Igg2b Apc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rat igg2b isotype control apc cyanine7  (Cytek Biosciences)
93
Cytek Biosciences rat igg2b isotype control apc cyanine7

Rat Igg2b Isotype Control Apc Cyanine7, supplied by Cytek Biosciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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κ apc cyanine7 rat igg2b  (Proteintech)
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Proteintech κ apc cyanine7 rat igg2b

κ Apc Cyanine7 Rat Igg2b, supplied by Proteintech, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cd11b  (Cedarlane)
91
Cedarlane cd11b

Cd11b, supplied by Cedarlane, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti cd8a  (Cedarlane)
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Cedarlane anti cd8a

Anti Cd8a, supplied by Cedarlane, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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apc mouse igg2b  (R&D Systems)
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R&D Systems apc mouse igg2b

Apc Mouse Igg2b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 4. Fc effector-enhanced anti-TREM2 mAb therapy reverses anti-PD-1 resistance (A) Frequency of live TREM2+ target cells following co-culture with mouse BMDMs and varying amounts of anti-TREM2-WT (mouse immuno- globulin G2a [IgG2a]) or anti-TREM2 (afucosylated mouse IgG2a) (n = 4/group). Samples were com- bined from two independent experiments. (B) ADCC reporter cell fluorescence following co- culture with or ADCC reporter cells and TREM2+- expressing target cells and varying amounts of anti-TREM2-WT, anti-TREM2, or appropriate iso- types (n = 2/group). (C) Tumor growth of EMT6-tumor bearing animals treated with 5 mg/kg of isotype or anti-TREM2. Vertical dotted lines indicate days when mAb dosing occurred (n = 10/group). (D) Violin plots of intratumoral normalized TAMs as a frequency of CD45+ cells from isotype- and anti- TREM2-treated EMT6 tumor-bearing mice 24, 72, and 128 h after mAb treatment. Samples were combined from two independent experiments (experiment 1, n = 4–7/group; experiment 2, n = 10/group). Unless specified otherwise, all experiments were performed two or more times. For graphs with error bars, mean ± SEM is shown. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. See also Figure S4.

Journal: Cell reports

Article Title: Targeting TREM2 on tumor-associated macrophages enhances immunotherapy.

doi: 10.1016/j.celrep.2021.109844

Figure Lengend Snippet: Figure 4. Fc effector-enhanced anti-TREM2 mAb therapy reverses anti-PD-1 resistance (A) Frequency of live TREM2+ target cells following co-culture with mouse BMDMs and varying amounts of anti-TREM2-WT (mouse immuno- globulin G2a [IgG2a]) or anti-TREM2 (afucosylated mouse IgG2a) (n = 4/group). Samples were com- bined from two independent experiments. (B) ADCC reporter cell fluorescence following co- culture with or ADCC reporter cells and TREM2+- expressing target cells and varying amounts of anti-TREM2-WT, anti-TREM2, or appropriate iso- types (n = 2/group). (C) Tumor growth of EMT6-tumor bearing animals treated with 5 mg/kg of isotype or anti-TREM2. Vertical dotted lines indicate days when mAb dosing occurred (n = 10/group). (D) Violin plots of intratumoral normalized TAMs as a frequency of CD45+ cells from isotype- and anti- TREM2-treated EMT6 tumor-bearing mice 24, 72, and 128 h after mAb treatment. Samples were combined from two independent experiments (experiment 1, n = 4–7/group; experiment 2, n = 10/group). Unless specified otherwise, all experiments were performed two or more times. For graphs with error bars, mean ± SEM is shown. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. See also Figure S4.

Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies anti-mouse XCR1 BV421 (clone ZET) Biolegend Cat # 148216; AB_2565230 anti-mouse F4/80 biotin (clone BM8) Biolegend Cat # 123106; AB_893501 Streptavidin BV510 Biolegend Cat # 405234 anti-mouse CD64 BV605 (clone X54-5/7.1) Biolegend Cat # 139323; AB_2629778 anti-mouse CD11c BV650 (clone N418) Biolegend Cat # 117339; AB_2562414 anti-mouse Ly-6C BV711 (clone HK1.4) Biolegend Cat # 128037; AB_2562630 anti-mouse CD90.2 BV785 (clone 30-H12) Biolegend Cat # 105331; AB_2562900 anti-mouse NKp46 BV785 (clone 29A1.4) Biolegend Cat # 137637; AB_2734201 anti-mouse/human CD45R/B220 BV785 (clone RA3-6B2) Biolegend Cat # 103246; AB_2563256 anti-mouse/human CD11b AF488 (clone M1/70) Biolegend Cat # 101217; AB_389305 anti-mouse CD45 PerCP/Cy5.5 (clone 30-F11) Biolegend Cat # 103132; AB_893340 anti-mouse Ly6G PE-e610 (clone 1A8-Ly6g) Invitrogen Cat # 61-9668-82; AB_2574679 anti-mouse CD24 PE/Cy7 (clone M1/69) Biolegend Cat # 101822; AB_756048 anti-mouse MHC-II AF700 (clone M5/ 114.15.2) Biolegend Cat # 107622; AB_493727 anti-mouse CD40 PE (clone 3/23) Biolegend Cat # 124610; AB_1134075 anti-mouse CD86 PE (clone GL-1) Biolegend Cat # 105008; AB_313151 Rat IgG2a, k PE isotype control PE (clone RTK2758) Biolegend Cat # 400508; AB_326530 anti-mouse/human TREM2 APC (clone 237920) R&D Systems Cat # FAB17291A; AB_884527 Rat IgG2b APC (clone 141945) R&D Systems Cat # IC013A; AB_357257 anti-mouse/human CD45R BV605 (clone RA3-6B2) Biolegend Cat # 103244; AB_2563312 anti-mouse NKp46 BV650 (clone clone 29A1.4) Biolegend Cat # 137635; AB_2734200 anti-mouse/human CD44 BV711 (clone IM7) Biolegend Cat # 103057; AB_2564214 anti-mouse CD279/PD-1 FITC (clone RMP1-30) Invitrogen Cat # 11-9981-82; AB_2564214 anti-mouse CD8a PerCP/Cy5.5 (clone 53-6.7) Biolegend Cat # 100734; AB_2075238 anti-mouse/human TOX PE (clone REA473) Miltenyi Biotec Cat # 130-120-716; AB_2801780 anti-mouse/human CD11b PE-e610 (clone M1/70) Invitrogen Cat # 61-0112-82; AB_2574528 anti-mouse CD4 PE/Cy7 (clone GK1.5) Biolegend Cat # 100422; AB_312707 anti-mouse FOXP3 A647 (clone MF-14) Biolegend Cat # 126408; AB_1089115 anti-mouse CD45 A700 (clone 30-F11) Biolegend Cat # 103128; AB_493715 anti-mouse TNF-a BV421 (clone MP6-XT22) Biolegend Cat # 506328; AB_2562902 anti-mouse IFNg BV605 (clone XMG1.2) Biolegend Cat # 505839; AB_2561438 anti-human CD45 PE (cone H130) Biolegend Cat # 304058; AB_2564156 (Continued on next page) Cell Reports 37, 109844, October 19, 2021 e1

Techniques: Co-Culture Assay, Expressing

Journal: Cell Reports Medicine

Article Title: Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

doi: 10.1016/j.xcrm.2023.101206

Figure Lengend Snippet:

Article Snippet: Rat IgG2b isotype control APC-Cyanine7 , Tonbo , Cat# 25-4031; RRID: AB_2621633.

Techniques: Control, Purification, Virus, Recombinant, CCK-8 Assay, Transfection, Protease Inhibitor, SYBR Green Assay, Saline, Lysis, Multiplex Assay, Cytotoxicity Assay, Cell Isolation, Enzyme-linked Immunosorbent Assay, Bicinchoninic Acid Protein Assay, Software